Description

1,2-Didecanoyl-Sn-Glycero-3-Phosphoethanolamine is a synthetic, saturated phospholipid belonging to the phosphatidylethanolamine (PE) class, specifically a 1,2-didecanoyl derivative. This compound is a critical building block in the formulation of advanced lipid-based delivery systems, offering superior control over membrane fluidity and stability. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors developing liposomal drug carriers, lipid nanoparticles for mRNA vaccines, and model membrane systems for biophysical studies.

Application

• Liposomal Drug Delivery: A key component for creating stable, uniform liposomes for encapsulating and delivering hydrophobic and hydrophilic active pharmaceutical ingredients (APIs).
• mRNA-LNP Formulations: Used in the lipid nanoparticle (LNP) matrix to enhance the stability, cellular uptake, and endosomal release of nucleic acid therapeutics.
• Biomimetic Membrane Research: Serves as a well-defined synthetic phospholipid for constructing model bilayers to study membrane protein interactions, permeability, and fusion mechanisms.
• Diagnostic Reagent Preparation: Employed in the development of diagnostic assays and imaging contrast agents that require specific lipid environments.
• Cell Culture & Transfection: Acts as a supplement in specialized cell culture media or as a component in non-viral transfection reagents.
• Cosmetic Nanotechnology: Incorporated into nanocarriers for the targeted and sustained delivery of active cosmetic ingredients in high-end skincare products.

Basic Information

Product Name	1,2-Didecanoyl-Sn-Glycero-3-Phosphoethanolamine
CAS No.	253685-27-7
Molecular Formula	C25H50NO8P
Molecular Weight	523.64 g/mol
Synonyms	1,2-Didecanoylphosphatidylethanolamine; Didecanoyl PE; PE(10:0/10:0); 1,2-Dicaprinoyl-sn-glycero-3-phosphoethanolamine; 3-sn-Phosphatidylethanolamine, 1,2-didecanoyl-; 1,2-Didecanoyl-sn-glycerol-3-phosphoethanolamine; DCPE; 1,2-Di-O-decanoyl-sn-glycero-3-phosphoethanolamine
EINECS	Contact for details

Quality Control

Our 1,2-Didecanoyl-Sn-Glycero-3-Phosphoethanolamine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical and research applications. A Certificate of Analysis (COA) detailing purity, related substances, and specific tests is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. This material is hygroscopic (moisture-sensitive). Allow the sealed container to reach room temperature before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Phase Transition Temperature (DSC)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.