Description

1-(4-Trifluoromethylphenyl)Piperidine-4-Carboxylic Acid Ethyl Ester is a high-purity, versatile pharmaceutical intermediate and building block. This compound is valued for its trifluoromethylphenyl and piperidine motifs, which are critical for modulating the biological activity, metabolic stability, and lipophilicity of target molecules. It is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging the trifluoromethyl group for enhanced efficacy.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies and library synthesis.
• Ligand and Receptor Probe Development: Employed in the creation of specialized chemical tools for biochemical and pharmacological research.

Basic Information

Product Name	1-(4-Trifluoromethylphenyl)Piperidine-4-Carboxylic Acid Ethyl Ester
CAS No.	253446-38-7
Molecular Formula	C15H18F3NO2
Molecular Weight	301.31 g/mol
Synonyms	Ethyl 1-[4-(Trifluoromethyl)phenyl]-4-piperidinecarboxylate; 4-Piperidinecarboxylic acid, 1-[4-(trifluoromethyl)phenyl]-, ethyl ester; 1-(4-(Trifluoromethyl)phenyl)piperidine-4-carboxylic acid ethyl ester; Ethyl 1-(4-trifluoromethylphenyl)piperidine-4-carboxylate; 1-(4-Trifluoromethylphenyl)-4-piperidinecarboxylic Acid Ethyl Ester; 253446-38-7; 1-(4-Trifluoromethylphenyl)piperidine-4-carboxylate ethyl ester
EINECS	Contact for details

Quality Control

Our 1-(4-Trifluoromethylphenyl)Piperidine-4-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.