Description

Piperazine, 1-(3,3-Dimethyl-1-Oxobutyl)- (9Ci) is a specialized piperazine derivative with a pivaloyl functional group, serving as a crucial building block in advanced organic synthesis. Its value lies in providing a sterically hindered amide moiety, which is instrumental for modulating the pharmacokinetic and physicochemical properties of target molecules. This high-purity intermediate is primarily needed by pharmaceutical R&D and fine chemical manufacturers for the development of novel active pharmaceutical ingredients (APIs) and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: Key synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs.
• API Synthesis: Used in the construction of complex molecules, potentially for therapeutic areas requiring sterically hindered amide linkages.
• Fine Chemical Production: Serves as a precursor in the manufacture of specialty chemicals, agrochemicals, and performance materials.
• Bioconjugation & Linker Chemistry: Potential use in creating chemical linkers or modifying biomolecules due to its reactive secondary amine and ketone groups.
• Academic & Industrial Research: Valuable reagent for synthetic organic chemistry research in both university and corporate laboratory settings.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.

Basic Information

Item	Detail
Product Name	Piperazine, 1-(3,3-Dimethyl-1-Oxobutyl)- (9Ci)
CAS No.	253175-46-1
Molecular Formula	C11H22N2O
Molecular Weight	198.31 g/mol
Synonyms	1-Pivaloylpiperazine; N-Pivaloylpiperazine; 1-(3,3-Dimethylbutanoyl)piperazine; 1-Piperazinecarboxamide, N,N-dimethyl-; Piperazine, 1-pivaloyl-; 253175-46-1; 1-(2,2-Dimethylpropionyl)piperazine
EINECS	Contact for details

Quality Control

Our Piperazine, 1-(3,3-Dimethyl-1-Oxobutyl)- (9Ci) is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specification parameters are provided with every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.