Description

1-Piperazinecarboxamide,n-(1,1-Dimethylethyl)-(9Ci) CAS NO 253175-42-7 is a high-purity, protected piperazine derivative serving as a critical building block in advanced organic synthesis. Its value lies in providing a versatile, tert-butyl-protected amide functional group that enables precise molecular construction while protecting reactive sites. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and anti-infective agents.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the piperazine moiety contributes to biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal complexation.
• Peptidomimetics Research: Employed in the design and synthesis of peptide analogs and conformationally restricted scaffolds for medicinal chemistry.
• Custom Chemical Synthesis: Provides a protected nitrogen source for multi-step synthetic routes in contract research and manufacturing (CRO/CMO).
• Material Science: Potential monomer or cross-linking agent in the development of specialty polymers with specific functional properties.

Basic Information

Product Name	1-Piperazinecarboxamide,n-(1,1-Dimethylethyl)-(9Ci)
CAS No.	253175-42-7
Molecular Formula	C9H19N3O
Molecular Weight	185.27 g/mol
Synonyms	N-(tert-Butyl)piperazine-1-carboxamide; 1-(tert-Butylcarbamoyl)piperazine; tert-Butyl 1-piperazinecarboxylate (common misnomer, correct IUPAC is carboxamide); N-tert-Butylpiperazine-1-carboxamide; 4-(tert-Butylaminocarbonyl)piperazine; Piperazine-1-carboxylic acid tert-butylamide; BOC-Piperazine (Note: This is a common but incorrect alias for the tert-butyl carbamate); 253175-42-7
EINECS	Contact for details

Quality Control

Our 1-Piperazinecarboxamide,n-(1,1-Dimethylethyl)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and production. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.