Description

C18 L-Erythro Ceramide (D18:1/18:0) is a high-purity, synthetic sphingolipid essential for advanced biomedical and cosmetic research. This specific ceramide, with its defined 18-carbon sphingosine base and 18-carbon stearic acid chain, serves as a critical standard and active ingredient for studying and modulating skin barrier function and cellular signaling pathways. It is indispensable for R&D and quality control in the pharmaceutical, dermatological, and premium skincare industries, where precise molecular structure and purity are paramount for efficacy and reproducibility.

Application

• Biomedical Research Standard: Used as a primary analytical standard in lipidomics, metabolomics, and sphingolipid signaling pathway studies.
• Skin Barrier Repair Formulations: A key active ingredient in high-end cosmetic and therapeutic skincare products designed to restore and enhance the skin's natural moisture barrier.
• Cell Biology & Biochemistry: Employed in in vitro studies to investigate ceramide-mediated processes such as apoptosis, cell differentiation, and stress responses.
• Pharmaceutical Development: Serves as a reference compound and potential excipient in the development of topical drug delivery systems targeting skin disorders.
• Quality Control & Assay Development: Essential for calibrating analytical instruments (HPLC, MS) and validating methods for ceramide quantification in complex matrices.

Basic Information

Product Name	C18 L-Erythro Ceramide (D18:1/18:0)
CAS No.	252039-52-4
Molecular Formula	C36H71NO3
Molecular Weight	565.97 g/mol
Synonyms	N-Stearoyl-D-erythro-sphingosine; N-(Octadecanoyl)-sphing-4-enine; Ceramide (d18:1/18:0); Ceramide NS; Ceramide 2; (2S,3R,4E)-2-Octadecanoylamino-4-octadecene-1,3-diol; D-erythro-C18-Ceramide (d18:1/18:0); L-Erythro-C18 Ceramide
EINECS	Contact for details

Quality Control

Our C18 L-Erythro Ceramide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for structural confirmation, and specific tests for residual solvents and heavy metals, to ensure it meets the stringent requirements of research and formulation. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability, consistency, and compliance with relevant standards.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the product to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.