Description

Tesaglitazar is a potent, dual-acting peroxisome proliferator-activated receptor (PPAR) agonist, specifically targeting the alpha and gamma subtypes. This compound is of significant interest in pharmaceutical research for its potential to modulate lipid and glucose metabolism. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutics for metabolic disorders, including type 2 diabetes and dyslipidemia.

Application

• Pharmaceutical Research & Development: Serves as a key reference standard and active pharmaceutical ingredient (API) in preclinical and clinical studies for metabolic diseases.
• Mechanistic Studies: Used in biochemical and pharmacological assays to investigate PPARα/γ dual agonism and its downstream effects on gene expression.
• Drug Discovery Programs: Acts as a lead compound or comparator in the design and screening of new PPAR modulators with improved efficacy and safety profiles.
• Academic Research: Employed in university and institutional labs to study insulin sensitization, adipocyte differentiation, and lipid homeostasis pathways.
• Analytical Method Development: Used as a high-purity standard for developing and validating HPLC, LC-MS, and other analytical methods for quality control.

Basic Information

Product Name	Tesaglitazar
CAS No.	251565-88-5
Molecular Formula	C₁₈H₁₆O₅S₂
Molecular Weight	376.45 g/mol
Synonyms	AZ-242; Galida; (S)-2-Ethoxy-3-[4-(2-{4-methanesulfonyloxy-2-propylphenoxy}ethyl)phenyl]propanoic acid; (S)-2-Ethoxy-3-[4-[2-(4-methanesulfonyloxy-2-propylphenoxy)ethyl]phenyl]propionic acid; PPARα/γ dual agonist
EINECS	Contact for details

Quality Control

Our Tesaglitazar is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identity confirmation, purity assay, and impurity profiling, to ensure it meets the stringent requirements for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single impurity ≤0.5%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.