Description

4-[4-(4-Fluorophenyl)Piperazino]Aniline is a high-purity, functionalized aniline derivative featuring a piperazine linker and a fluorophenyl group, making it a versatile and valuable building block in advanced organic synthesis. Its molecular architecture is specifically designed to serve as a key intermediate in the development of active pharmaceutical ingredients (APIs) and other high-value specialty chemicals. This compound is essential for research and production teams in the pharmaceutical, agrochemical, and material science industries seeking to incorporate complex amine functionalities into novel molecular entities.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, due to its piperazine-aniline pharmacophore.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, where the fluorine atom and amine group can enhance biological activity and environmental stability.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of advanced polymers, dyes, and photoactive materials.
• Chemical Research & Development: Employed as a standard or building block in medicinal chemistry and process chemistry for structure-activity relationship (SAR) studies and route scouting.
• Ligand Synthesis: Useful for preparing complex ligands for catalysis or metal-organic frameworks (MOFs) in academic and industrial research settings.

Basic Information

Product Name	4-[4-(4-Fluorophenyl)Piperazino]Aniline
CAS No.	251097-69-5
Molecular Formula	C16H18FN3
Molecular Weight	271.34 g/mol
Synonyms	1-(4-Aminophenyl)-4-(4-fluorophenyl)piperazine; 4-[4-(4-Fluorophenyl)-1-piperazinyl]aniline; 4-(4-Fluorophenyl)piperazinoaniline; N-(4-Aminophenyl)-N'-(4-fluorophenyl)piperazine; 4-(4-Fluorophenyl)-1-(4-aminophenyl)piperazine; 251097-69-5; 4-(4-Fluorophenyl)piperazin-1-yl]aniline
EINECS	Contact for details

Quality Control

Every batch of 4-[4-(4-Fluorophenyl)Piperazino]Aniline is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing key parameters such as assay, related substances, and residual solvents. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture and contamination. Store away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.