Description

Imiglitazar CAS NO 250601-04-8 is a high-purity pharmaceutical intermediate and research chemical belonging to the class of dual peroxisome proliferator-activated receptor (PPAR) α/γ agonists. This compound is of significant interest for its role in metabolic research and the development of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers engaged in the synthesis of advanced drug candidates targeting diabetes and related metabolic disorders.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of advanced investigational drugs targeting metabolic diseases.
• Biomedical Research: Used as a reference standard and active compound in in vitro and in vivo studies to investigate PPAR receptor pharmacology.
• Drug Discovery & Development: Serves as a crucial starting material or intermediate in medicinal chemistry programs for developing new antidiabetic agents.
• Reference Standard: Employed in analytical laboratories for method development, validation, and quality control testing of related pharmaceutical products.
• Preclinical Studies: Utilized in metabolic disease model research to evaluate efficacy and mechanism of action.

Basic Information

Item	Detail
Product Name	Imiglitazar
CAS No.	250601-04-8
Molecular Formula	C24H21NO4S
Molecular Weight	419.49 g/mol
Synonyms	Imiglitazar; 4-[[(2S)-2-Ethoxy-3-[4-[2-(methylsulfonyloxy)ethoxy]phenyl]propyl]thio]-2-methylphenoxyacetic Acid; YM-440; PPAR α/γ Agonist YM440; (S)-4-(2-Ethoxy-3-(4-(2-(methylsulfonyloxy)ethoxy)phenyl)propylthio)-2-methylphenoxyacetic Acid
EINECS	Contact for details

Quality Control

Our Imiglitazar is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification by spectroscopic methods (IR, NMR), purity determination by HPLC, and control of related substances and residual solvents. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and development grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.