Description

Cyclopropyl-(S)-Piperidin-3-Yl-Carbamic Acid tert-Butyl Ester is a high-purity chiral building block and advanced pharmaceutical intermediate. This compound is of significant value for medicinal chemistry research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily needed by pharmaceutical R&D laboratories, contract research and manufacturing organizations (CROs/CMOs), and fine chemical suppliers targeting the life sciences sector.

Application

• Pharmaceutical Intermediate: Key chiral synthon in the research and development of new therapeutic agents.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization for drug discovery programs.
• API Synthesis: Serves as a critical building block in the multi-step synthesis of complex target molecules, particularly those containing piperidine and cyclopropyl motifs.
• Preclinical Research: Employed in the synthesis of compounds for pharmacological screening and toxicology studies.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or precursor in stereoselective synthetic routes.
• Chemical Reference Standard: Serves as a high-purity standard for analytical method development and quality control in pharmaceutical manufacturing.

Basic Information

Item	Details
Product Name	Cyclopropyl-(S)-Piperidin-3-Yl-Carbamic Acid tert-Butyl Ester
CAS No.	250275-25-3
Molecular Formula	C13H24N2O2
Molecular Weight	240.34 g/mol
Synonyms	(S)-tert-Butyl 3-(cyclopropylcarbamoyl)piperidine-1-carboxylate; (S)-1-Boc-3-(cyclopropylcarbamoyl)piperidine; (S)-N-Cyclopropyl-1-(tert-butoxycarbonyl)piperidine-3-carboxamide; (S)-1-Boc-3-piperidinecarboxylic acid cyclopropylamide; (S)-N-Cyclopropyl-1-Boc-piperidine-3-carboxamide; tert-Butyl (3S)-3-[(cyclopropylamino)carbonyl]-1-piperidinecarboxylate; (S)-1-Boc-piperidine-3-carboxylic acid cyclopropylamide
EINECS	Contact for details

Quality Control

Our Cyclopropyl-(S)-Piperidin-3-Yl-Carbamic Acid tert-Butyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting standards for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.