Description

(4,7,10-Tri-Boc-1,4,7,10-Tetraazacyclodecan-1-Yl)Acetic Acid is a high-purity, protected macrocyclic intermediate of significant value in advanced organic synthesis. This compound is crucial for researchers and manufacturers requiring precise molecular scaffolds for complex ligand development. It is primarily utilized in the pharmaceutical and chemical research sectors for the synthesis of specialized chelating agents, catalysts, and diagnostic imaging precursors.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing macrocyclic chelators used in MRI contrast agents and radiopharmaceuticals.
• Ligand Synthesis: Precursor for creating sophisticated ligands for metal catalysis and coordination chemistry.
• Chemical Research: Used in academic and industrial R&D for developing novel functionalized cyclen derivatives.
• Diagnostic Agent Development: Intermediate in the production of compounds for medical imaging and diagnostic applications.
• Material Science: Building block for functional polymers and advanced materials requiring specific metal-binding sites.

Basic Information

Product Name	(4,7,10-Tri-Boc-1,4,7,10-Tetraazacyclodecan-1-Yl)Acetic Acid
CAS No.	247193-74-4
Molecular Formula	C27H49N4O8
Molecular Weight	557.70 g/mol
Synonyms	1,4,7,10-Tetraazacyclododecane-1-acetic acid, 4,7,10-tris(1,1-dimethylethyl) 1,4,7,10-tetracarbamate; 1-Carboxymethyl-4,7,10-tris(tert-butoxycarbonyl)-1,4,7,10-tetraazacyclododecane; Tri-Boc-DO3A-tBu-COOH; DO3A-tris(t-butyl ester); Tris-Boc-protected cyclen acetic acid; 1,4,7-Tris(tert-butoxycarbonyl)-1,4,7,10-tetraazacyclododecane-10-acetic acid; 4,7,10-Tri-Boc-1,4,7,10-tetraazacyclododecane-1-acetic acid
EINECS	Contact for details

Quality Control

Our (4,7,10-Tri-Boc-1,4,7,10-Tetraazacyclodecan-1-Yl)Acetic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our customers' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.