Description

4-Pentenoicacid,2-Amino-4-Fluoro-2-Methyl-,(2R)-(9Ci) is a chiral, fluorinated amino acid derivative of significant interest in advanced organic synthesis. This compound matters as a sophisticated building block for constructing complex molecules with specific stereochemistry and bioactivity. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, particularly in medicinal chemistry programs targeting enzyme inhibition.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, especially protease inhibitors and other enzyme-targeted therapies.
• Agrochemical Synthesis: Used in the creation of advanced, fluorinated active ingredients for crop protection products, leveraging the fluorine atom's ability to modulate bioavailability and stability.
• Peptidomimetics Research: Serves as a non-natural amino acid analog for constructing peptidomimetic compounds in biochemical and pharmacological studies.
• Chemical Biology Probes: Employed in the synthesis of labeled or tagged molecules used to study biological pathways and protein interactions.
• Asymmetric Catalysis Ligand Precursor: Potential use as a starting material for synthesizing chiral ligands or organocatalysts used in enantioselective reactions.

Basic Information

Product Name	4-Pentenoicacid,2-Amino-4-Fluoro-2-Methyl-,(2R)-(9Ci)
CAS No.	247122-88-9
Molecular Formula	C6H10FNO2
Molecular Weight	147.15 g/mol
Synonyms	(2R)-2-Amino-4-fluoro-2-methyl-4-pentenoic acid; (R)-2-Amino-4-fluoro-2-methylpent-4-enoic acid; 2-Amino-4-fluoro-2-methyl-4-pentenoic acid, (2R)-; 4-Pentenoic acid, 2-amino-4-fluoro-2-methyl-, (2R)-; (R)-4-Fluoro-2-methyl-2-aminopent-4-enoic acid; 247122-88-9; (2R)-2-Amino-4-fluoro-2-methyl-4-pentenoate
EINECS	Contact for details

Quality Control

Our production of 4-Pentenoicacid,2-Amino-4-Fluoro-2-Methyl-,(2R)-(9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chiral purity verification by HPLC. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, assay, enantiomeric excess, and impurity profiles to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.