Description

(R)-(2,3-Dimethoxyphenyl)-4-Piperidinemethanol is a chiral piperidine derivative of significant interest in advanced organic synthesis. This compound serves as a crucial chiral building block and intermediate for the development of active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily needed by pharmaceutical R&D departments, contract research organizations (CROs), and manufacturers of specialty chemicals targeting neurological and receptor-based therapeutics.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Asymmetric Synthesis: Employed as a chiral auxiliary or resolving agent in stereoselective chemical reactions to produce enantiomerically pure compounds.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Fine Chemical Production: Intermediate in the manufacture of complex, high-value specialty chemicals and advanced materials.
• Reference Standard: Serves as an analytical standard for quality control and regulatory compliance in API manufacturing.

Basic Information

Product Name	(R)-(2,3-Dimethoxyphenyl)-4-Piperidinemethanol
CAS No.	243640-19-9
Molecular Formula	C14H21NO3
Molecular Weight	251.32 g/mol
Synonyms	(R)-2,3-Dimethoxy-α-((4-piperidinyl)methyl)benzenemethanol; (R)-4-((2,3-Dimethoxyphenyl)(hydroxy)methyl)piperidine; (R)-α-(2,3-Dimethoxyphenyl)-4-piperidinemethanol; (R)-(-)-2,3-Dimethoxy-α-(4-piperidinylmethyl)benzyl Alcohol; (R)-(-)-α-(2,3-Dimethoxyphenyl)-4-piperidinemethanol; (R)-enantiomer of 243640-19-9; 4-Piperidinemethanol, α-(2,3-dimethoxyphenyl)-, (αR)-
EINECS	Contact for details

Quality Control

Our (R)-(2,3-Dimethoxyphenyl)-4-Piperidinemethanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. A detailed Certificate of Analysis (COA) providing specifications for identity, purity, and enantiomeric excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.