Description

5-(tert-Butyl)Pyrazine-2-Carboxylic Acid is a high-purity pyrazine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique steric and electronic properties imparted by the tert-butyl group, which are essential for modulating the activity and selectivity of target molecules. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the pyrazine core contributes to biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic semiconductors, conductive polymers, and other functional organic materials.
• Flavor & Fragrance Chemistry: Acts as an intermediate for synthesizing complex aroma chemicals due to the pyrazine ring's role in nutty, roasted flavor profiles.
• Academic & Contract Research: A valuable reagent for methodological studies and the exploration of new chemical reactions in academic and industrial R&D settings.

Basic Information

Product Name	5-(tert-Butyl)Pyrazine-2-Carboxylic Acid
CAS No.	242813-48-5
Molecular Formula	C9H12N2O2
Molecular Weight	180.21 g/mol
Synonyms	5-tert-Butylpyrazine-2-carboxylic acid; 2-Pyrazinecarboxylic acid, 5-(1,1-dimethylethyl)-; 5-(1,1-Dimethylethyl)-2-pyrazinecarboxylic acid; 5-(tert-Butyl)-2-pyrazinecarboxylic acid; 5-tert-Butyl-2-pyrazinecarboxylic acid; 5-(tert-Butyl)pyrazine-2-carboxylate; 242813-48-5; tert-Butylpyrazinecarboxylic acid
EINECS	Contact for details

Quality Control

Our production of 5-(tert-Butyl)Pyrazine-2-Carboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.