Description

2,8-Diaza-Spiro[4.5]Decane-8-Carboxylic Acid tert-Butyl Ester is a high-value, nitrogen-containing spirocyclic building block used in advanced organic synthesis. This compound is a critical intermediate for medicinal chemistry research, enabling the construction of complex molecular architectures. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers for developing novel active pharmaceutical ingredients (APIs) and other biologically active compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly for central nervous system (CNS) and other therapeutic targets.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization programs to explore structure-activity relationships (SAR) due to its rigid, three-dimensional spirocyclic scaffold.
• Library Synthesis: Employed in the generation of diverse compound libraries for high-throughput screening (HTS) in drug discovery.
• Chemical Biology Probes: Serves as a core structure for developing molecular probes to study biological pathways and protein function.
• Agrochemical Research: Potential intermediate in the development of novel crop protection agents and pesticides.
• Material Science: Can be utilized in the synthesis of specialty polymers or ligands for catalysis.

Basic Information

Product Name	2,8-Diaza-Spiro[4.5]Decane-8-Carboxylic Acid tert-Butyl Ester
CAS No.	236406-39-6
Molecular Formula	C13H24N2O2
Molecular Weight	240.34 g/mol
Synonyms	tert-Butyl 2,8-diaza-spiro[4.5]decane-8-carboxylate; 2,8-Diaza-spiro[4.5]decane-8-carboxylic acid 1,1-dimethylethyl ester; 8-Boc-2,8-diaza-spiro[4.5]decane; 2,8-Diazaspiro[4.5]decane-8-carboxylic acid tert-butyl ester; 8-(tert-Butoxycarbonyl)-2,8-diazaspiro[4.5]decane; Boc-2,8-diazaspiro[4.5]decane; 1,1-Dimethylethyl 2,8-diazaspiro[4.5]decane-8-carboxylate
EINECS	Contact for details

Quality Control

Our 2,8-Diaza-Spiro[4.5]Decane-8-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our commitment to quality supports your research and development needs with reliable, high-purity building blocks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.