Description

2-Piperazinecarboxylicacid,6-Oxo-,Methylester,(2S)-(9Ci) is a high-purity chiral piperazine derivative, a crucial building block in modern pharmaceutical synthesis. Its defined stereochemistry and functional groups make it an essential intermediate for constructing complex molecules with specific biological activity. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated heterocyclic chemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel drug candidates, particularly for central nervous system (CNS) and antiviral therapies.
• Peptidomimetic Chemistry: Serves as a constrained amino acid analog for designing and synthesizing peptide-like molecules with enhanced metabolic stability and bioavailability.
• Ligand and Catalyst Development: Used in the preparation of chiral ligands and organocatalysts for asymmetric synthesis applications.
• Chemical Biology Research: Employed as a molecular scaffold or probe in studying enzyme mechanisms and protein-protein interactions.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for client projects.
• Reference Standard: Sourced for analytical purposes as a high-purity reference standard in quality control laboratories.

Basic Information

Product Name	2-Piperazinecarboxylicacid,6-Oxo-,Methylester,(2S)-(9Ci)
CAS No.	234109-21-8
Molecular Formula	C7H12N2O3
Molecular Weight	172.18 g/mol
Synonyms	(2S)-6-Oxo-2-piperazinecarboxylic acid methyl ester; Methyl (2S)-6-oxopiperazine-2-carboxylate; (S)-Methyl 6-oxopiperazine-2-carboxylate; (S)-Methyl 2,3,4,5-tetrahydropyrazine-2-carboxylate 1-oxide; L-6-Oxopiperazine-2-carboxylic acid methyl ester; (S)-1-Oxo-1,2,3,4-tetrahydropyrazine-2-carboxylic acid methyl ester; 234109-21-8; (2S)-6-Oxopiperazine-2-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our 2-Piperazinecarboxylicacid,6-Oxo-,Methylester,(2S)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the stringent requirements for pharmaceutical R&D and cGMP applications. A detailed Certificate of Analysis (COA) providing identity, purity, and impurity profiles is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for prolonged operations to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.