Description

tert-Butyl 4-(2-Aminoethyl)-3-oxopiperazine-1-carboxylate is a high-purity, protected piperazine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its bifunctional nature, featuring both a reactive aminoethyl side chain and a tert-butyloxycarbonyl (Boc) protected amine, enabling precise and sequential chemical modifications. It is primarily utilized by pharmaceutical and biotechnology R&D teams for the development of novel active pharmaceutical ingredients (APIs), particularly in the synthesis of complex heterocyclic molecules and targeted drug candidates.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders and oncology.
• Peptidomimetic Chemistry: Used to introduce constrained piperazine scaffolds into peptide backbones to enhance metabolic stability and receptor binding affinity.
• Library Synthesis for Drug Discovery: Employed in parallel and combinatorial chemistry to generate diverse compound libraries for high-throughput screening (HTS).
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and contract research & manufacturing services (CRAMS).

Basic Information

Product Name	tert-Butyl 4-(2-Aminoethyl)-3-oxopiperazine-1-carboxylate
CAS No.	234108-58-8
Molecular Formula	C11H21N3O3
Molecular Weight	243.31 g/mol
Synonyms	1-Boc-4-(2-aminoethyl)-3-oxopiperazine; 1-(tert-Butoxycarbonyl)-4-(2-aminoethyl)-3-oxopiperazine; 4-(2-Aminoethyl)-3-oxo-1-piperazinecarboxylic acid tert-butyl ester; tert-Butyl 4-(2-aminoethyl)-3-oxo-1-piperazinecarboxylate; 3-Oxo-4-(2-aminoethyl)piperazine-1-carboxylic acid tert-butyl ester; 1-N-Boc-4-(2-aminoethyl)-3-oxopiperazine; BOC-AEP; 234108-58-8
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(2-Aminoethyl)-3-oxopiperazine-1-carboxylate is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and pre-clinical development phases.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.