Description

3,5-Dichloroisonicotinoyl Chloride is a high-purity, reactive chemical intermediate characterized by its acid chloride functionality and halogenated pyridine core. This compound matters for its critical role as a versatile building block in the synthesis of complex molecules, enabling the introduction of the 3,5-dichloroisonicotinate moiety. It is primarily needed by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, leveraging its halogenated structure for enhanced biological activity.
• Chemical Research & Development: Serves as a versatile reagent in academic and industrial R&D labs for constructing complex heterocyclic compounds and exploring new chemical spaces.
• Material Science Precursor: Potential use in the synthesis of functionalized ligands for metal-organic frameworks (MOFs) or advanced polymeric materials.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing specialized fine chemicals on scale.

Basic Information

Product Name	3,5-Dichloroisonicotinoyl Chloride
CAS No.	229328-97-6
Molecular Formula	C7H2Cl3NO
Molecular Weight	230.46 g/mol
Synonyms	3,5-Dichloropyridine-4-carbonyl chloride; 3,5-Dichloroisonicotinic acid chloride; 3,5-Dichloro-4-pyridinecarbonyl chloride; 4-Pyridinecarbonyl chloride, 3,5-dichloro-; Isonicotinoyl chloride, 3,5-dichloro-; 3,5-Dichloro-4-pyridylcarbonyl chloride
EINECS	Contact for details

Quality Control

Our 3,5-Dichloroisonicotinoyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality parameters. Our commitment to quality supports compliance with cGMP and ISO standards where required for advanced synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and reacts with strong acids/organic solvents; ensure the container is kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat, sparks, open flames, and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.