Description

4-Amino-1-Methyl-Piperidine-4-Carboxylic Acid Methyl Ester is a high-purity, functionalized piperidine derivative that serves as a critical chiral building block and intermediate in advanced organic synthesis. Its unique structure, featuring both amino and ester functionalities on the same carbon, makes it a versatile scaffold for constructing complex molecules with high stereochemical control. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of potent drug candidates, particularly in central nervous system (CNS) and antiviral therapeutic areas.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging its piperidine core for biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Custom Synthesis Building Block: Provides a versatile starting point for contract research organizations (CROs) and custom synthesis houses to create bespoke compounds for clients.
• Academic Research: Used in universities and research institutes for methodological development in organic chemistry and medicinal chemistry projects.

Basic Information

Product Name	4-Amino-1-Methyl-Piperidine-4-Carboxylic Acid Methyl Ester
CAS No.	228252-34-4
Molecular Formula	C9H18N2O2
Molecular Weight	186.25 g/mol
Synonyms	1-Methyl-4-aminoisonipecotic acid methyl ester; Methyl 4-amino-1-methyl-4-piperidinecarboxylate; 4-Amino-1-methylpiperidine-4-carboxylic acid methyl ester; 4-Piperidinecarboxylic acid, 4-amino-1-methyl-, methyl ester; 228252-34-4; 1-Methyl-4-aminopiperidine-4-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our 4-Amino-1-Methyl-Piperidine-4-Carboxylic Acid Methyl Ester is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring suitability for demanding research and pre-clinical development phases.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). For long-term storage, consider using desiccants or storing under an inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.