Description

5-Isobenzofurancarbonylchloride,1,3-Dihydro-1-Oxo-(9Ci) is a specialized organic intermediate featuring a reactive acid chloride group on an isobenzofuranone scaffold. This compound matters for its role as a key building block in the synthesis of complex heterocyclic molecules and active pharmaceutical ingredients (APIs). It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the isobenzofuranone core contributes to biological activity.
• Organic Ligand & Catalyst Development: Serves as a starting material for creating complex ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer & Material Science: Employed in the development of specialty polymers, dyes, and functional materials requiring specific heterocyclic architectures.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry, including new coupling and cyclization reactions.

Basic Information

Product Name	5-Isobenzofurancarbonylchloride,1,3-Dihydro-1-Oxo-(9Ci)
CAS No.	227954-90-7
Molecular Formula	C9H5ClO3
Molecular Weight	196.59 g/mol
Synonyms	1,3-Dihydro-1-oxo-5-isobenzofurancarbonyl chloride; 5-Chlorocarbonylphthalide; 1-Oxo-1,3-dihydroisobenzofuran-5-carbonyl chloride; Phthalide-5-carbonyl chloride; 5-Phthalidecarbonyl chloride; 5-(Chlorocarbonyl)phthalide; 1-Oxo-1,3-dihydro-2-benzofuran-5-carbonyl chloride; 5-Carboxyphthalide chloride
EINECS	Contact for details

Quality Control

Our 5-Isobenzofurancarbonylchloride,1,3-Dihydro-1-Oxo-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure high purity and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.