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3-[1-[[(3μ-Nitro[1,1μ-Biphenyl]-4-Yl)Oxy]Methyl]-3-(4-Pyridinyl)Propyl]-2,4-Thiazolidinedione CAS NO 227088-94-0


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CAS No.:227088-94-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

3-[1-[[(3μ-Nitro[1,1μ-Biphenyl]-4-Yl)Oxy]Methyl]-3-(4-Pyridinyl)Propyl]-2,4-Thiazolidinedione is a high-purity, synthetic organic compound of significant interest in advanced pharmaceutical research and development. This molecule serves as a critical intermediate or reference standard for the synthesis and study of novel therapeutic agents, particularly those targeting metabolic and inflammatory pathways. It is essential for research organizations, pharmaceutical developers, and fine chemical manufacturers engaged in the creation of new drug candidates.

Application

  • Pharmaceutical Intermediate: A key building block in the synthesis of potential thiazolidinedione-based drug candidates for metabolic disorders.
  • Research & Development (R&D): Used as a reference standard or lead compound in medicinal chemistry programs for structure-activity relationship (SAR) studies.
  • Biochemical Research: Employed in in-vitro and in-vivo studies to investigate biological pathways related to peroxisome proliferator-activated receptors (PPARs).
  • Fine Chemical Synthesis: Serves as a specialized intermediate for the production of complex, high-value organic molecules in contract manufacturing.
  • Analytical Standard: Provides a certified reference material for quality control and analytical method development in pharmaceutical laboratories.

Basic Information

Product Name 3-[1-[[(3μ-Nitro[1,1μ-Biphenyl]-4-Yl)Oxy]Methyl]-3-(4-Pyridinyl)Propyl]-2,4-Thiazolidinedione
CAS No. 227088-94-0
Molecular Formula C24H21N3O5S
Molecular Weight 463.51 g/mol
Synonyms 3-[1-[[(3'-Nitro[1,1'-biphenyl]-4-yl)oxy]methyl]-3-(4-pyridinyl)propyl]-2,4-thiazolidinedione; 3-(1-{[(3'-Nitro[1,1'-biphenyl]-4-yl)oxy]methyl}-3-(pyridin-4-yl)propyl)-1,3-thiazolidine-2,4-dione; 227088-94-0; 3-[1-[[(3'-Nitro-4-biphenylyl)oxy]methyl]-3-(4-pyridyl)propyl]-2,4-thiazolidinedione; Nitrobiphenyl-thiazolidinedione derivative; 4-[3-(2,4-Dioxothiazolidin-3-yl)-1-[[(3'-nitro[1,1'-biphenyl]-4-yl)oxy]methyl]propyl]pyridine
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Quality Control

Our 3-[1-[[(3μ-Nitro[1,1μ-Biphenyl]-4-Yl)Oxy]Methyl]-3-(4-Pyridinyl)Propyl]-2,4-Thiazolidinedione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed in a desiccated environment and handled under conditions that minimize exposure to ambient light and humidity to maintain stability and purity.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 10 ppm
Single Unknown Impurity (HPLC) ≤ 0.5%
Total Impurities (HPLC) ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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