Description

Piperazine, 2,6-Dimethyl-1-(1-Methylethyl)-, (2R,6S)-Rel- (9Ci) is a high-purity, stereochemically defined piperazine derivative, serving as a critical chiral building block in advanced organic synthesis. Its precise stereochemistry and structural features make it an invaluable intermediate for developing enantiomerically pure pharmaceuticals and fine chemicals. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to create novel active ingredients with high specificity.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of central nervous system (CNS) agents, antivirals, and receptor modulators.
• Agrochemical Research: Used in the creation of novel, enantiomerically pure pesticides and herbicides where specific stereochemistry is crucial for biological activity and environmental safety.
• Catalyst Ligand Precursor: Serves as a starting material for synthesizing sophisticated chiral ligands used in asymmetric catalysis, enhancing the efficiency of chemical manufacturing processes.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex natural products, flavors, fragrances, and other high-value specialty chemicals requiring defined stereocenters.
• Academic & Industrial R&D: A valuable tool for medicinal chemistry programs and process chemistry development in both university laboratories and corporate R&D facilities.

Basic Information

Product Name	Piperazine, 2,6-Dimethyl-1-(1-Methylethyl)-, (2R,6S)-Rel- (9Ci)
CAS No.	226575-84-4
Molecular Formula	C9H20N2
Molecular Weight	156.27 g/mol
Synonyms	rel-(2R,6S)-2,6-Dimethyl-1-(propan-2-yl)piperazine; (2R,6S)-2,6-Dimethyl-1-isopropylpiperazine; 1-Isopropyl-2,6-dimethylpiperazine (stereoisomer); 2,6-Dimethyl-1-(1-methylethyl)piperazine, (2R,6S)-rel-; 226575-84-4; A chiral 2,6-dimethylpiperazine derivative; Isopropyl-2,6-dimethylpiperazine
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our chiral intermediates. Production follows current Good Manufacturing Practice (cGMP) principles where applicable, and each batch is analyzed to confirm identity, purity, and enantiomeric excess. Certificates of Analysis (COA) are provided with every shipment, detailing key parameters such as assay, chiral purity by HPLC, and residual solvent content. Our commitment ensures the reliable consistency required for your critical synthetic pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.