Description

1-tert-Butyl 4-Ethyl 4-(4-Fluorophenylsulfonyl)Piperidine-1,4-Dicarboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its piperidine core and fluorophenylsulfonyl functional group. This compound is critical for research and development in medicinal chemistry, serving as a key building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of new therapeutic agents, particularly those targeting central nervous system and metabolic disorders.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the multi-step synthesis of complex drug candidates and novel APIs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new drug discovery programs.
• Process Chemistry Development: Serves as a critical starting material or intermediate for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for the bespoke production of specialized compounds for clients.
• Chemical Reference Standard: Can be used as a high-purity analytical standard for method development and quality control in pharmaceutical analysis.

Basic Information

Product Name	1-tert-Butyl 4-Ethyl 4-(4-Fluorophenylsulfonyl)Piperidine-1,4-Dicarboxylate
CAS No.	226396-63-0
Molecular Formula	C19H26FNO6S
Molecular Weight	415.48 g/mol
Synonyms	1-tert-Butyl 4-ethyl piperidine-1,4-dicarboxylate 4-(4-fluorophenylsulfonyl) derivative; 4-(4-Fluorobenzenesulfonyl)-1,4-piperidinedicarboxylic acid 1-(1,1-dimethylethyl) 4-ethyl ester; 4-(4-Fluorophenylsulfonyl)piperidine-1,4-dicarboxylic acid tert-butyl ethyl ester; tert-Butyl ethyl 4-(4-fluorophenylsulfonyl)piperidine-1,4-dicarboxylate; Ethyl 1-tert-butyl 4-(4-fluorophenylsulfonyl)piperidine-1,4-dicarboxylate; CAS 226396-63-0; FC-Intermediate (common in research contexts)
EINECS	Contact for details

Quality Control

Our 1-tert-Butyl 4-Ethyl 4-(4-Fluorophenylsulfonyl)Piperidine-1,4-Dicarboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity (typically >97% by HPLC), identity confirmation (by IR, NMR), and impurity profile is provided with each shipment to support your quality and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.