Description

1-Piperazinecarboxylic Acid, 4-(3-Pyridinyl)-, 1,1-Dimethylethyl Ester is a high-purity, protected piperazine derivative of significant importance in modern pharmaceutical research and development. This compound serves as a critical building block (synthon) for the synthesis of complex molecules, particularly in medicinal chemistry. It is primarily needed by R&D laboratories and production facilities in the pharmaceutical and biotechnology sectors for creating novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Synthesis: Incorporated into the production of complex molecules where the piperazine and pyridine moieties are required for biological activity.
• Chemical Biology: Employed in the development of chemical probes and tool compounds for studying biological pathways and protein function.
• Custom Synthesis: Serves as a starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.
• Library Synthesis: Used in combinatorial chemistry to generate diverse compound libraries for high-throughput screening.

Basic Information

Product Name	1-Piperazinecarboxylic Acid, 4-(3-Pyridinyl)-, 1,1-Dimethylethyl Ester
CAS No.	223797-47-5
Molecular Formula	C14H21N3O2
Molecular Weight	263.34 g/mol
Synonyms	tert-Butyl 4-(pyridin-3-yl)piperazine-1-carboxylate; 4-(3-Pyridinyl)-1-piperazinecarboxylic acid 1,1-dimethylethyl ester; 3-(4-Boc-piperazin-1-yl)pyridine; Boc-3-pyridylpiperazine; N-Boc-3-(1-piperazinyl)pyridine; 1-Boc-4-(3-pyridyl)piperazine; tert-Butyl 4-(3-pyridyl)piperazine-1-carboxylate
EINECS	Contact for details

Quality Control

Our 1-Piperazinecarboxylic Acid, 4-(3-Pyridinyl)-, 1,1-Dimethylethyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with the standards expected for pharmaceutical-grade intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.