Description

Piperazine, 3,3-Dimethyl-1-Phenyl- (9Ci) is a specialized piperazine derivative, a key heterocyclic building block valued for its structural complexity and functional versatility in advanced synthesis. This compound is essential for research and development chemists seeking to introduce a sterically hindered, phenyl-substituted piperazine moiety into novel molecular architectures. It is primarily utilized in the pharmaceutical and agrochemical industries for the development of active ingredients and fine chemical intermediates.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, particularly for central nervous system (CNS) targets, receptor modulators, and enzyme inhibitors.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, where the piperazine core can contribute to biological activity.
• Ligand and Catalyst Development: Acts as a building block for creating complex ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of specialty polymers, dyes, and photoactive materials requiring specific nitrogen-containing heterocycles.
• Chemical Biology Probe Synthesis: Utilized to create molecular probes for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: A key starting material for custom synthesis projects requiring bespoke, high-purity heterocyclic compounds.

Basic Information

Product Name	Piperazine, 3,3-Dimethyl-1-Phenyl- (9Ci)
CAS No.	223786-43-4
Molecular Formula	C12H18N2
Molecular Weight	190.29 g/mol
Synonyms	1-Phenyl-3,3-dimethylpiperazine; 3,3-Dimethyl-1-phenylpiperazine; N-Phenyl-3,3-dimethylpiperazine; 1-Phenyl-3,3-dimethyl-piperazine; 3,3-Dimethyl-N-phenylpiperazine; Piperazine, 3,3-dimethyl-1-phenyl-; 223786-43-4 (CAS)
EINECS	Contact for details

Quality Control

Our Piperazine, 3,3-Dimethyl-1-Phenyl- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent lot-to-lot quality. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and impurity profiles. We support development and scale-up projects with custom synthesis capabilities to meet specific purity or packaging requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.