Description

Piperazine, 1-(3-Azetidinyl)-4-(4-Fluorophenyl)-, Hydrochloride is a high-purity, specialized organic salt of significant interest in advanced pharmaceutical research and development. This compound serves as a critical pharmacologically active intermediate or building block for synthesizing novel therapeutic agents. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the discovery of new drug candidates, particularly within central nervous system (CNS) and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) targets.
• Active Pharmaceutical Ingredient (API) Development: Used in research for developing new APIs that leverage the piperazine-azetidine scaffold.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Preclinical Studies: Employed in the preparation of compounds for pharmacological screening and toxicological evaluation.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up of complex molecules for clinical trials.
• Reference Standard: Can be utilized as an analytical standard for quality control and method development in API manufacturing.

Basic Information

Item	Detail
Product Name	Piperazine, 1-(3-Azetidinyl)-4-(4-Fluorophenyl)-, Hydrochloride
CAS No.	223382-02-3
Molecular Formula	C13H18FN3·HCl
Molecular Weight	263.76 g/mol (Free base: 227.30 g/mol)
Synonyms	1-(Azetidin-3-yl)-4-(4-fluorophenyl)piperazine hydrochloride; 4-(4-Fluorophenyl)-1-(azetidin-3-yl)piperazine hydrochloride; 3-[4-(4-Fluorophenyl)piperazin-1-yl]azetidine hydrochloride; 1-(3-Azetidinyl)-4-(4-fluorophenyl)piperazine HCl; 4-(4-Fluorophenyl)-1-(azetidin-3-yl)piperazine HCl; Azetidine, 3-[4-(4-fluorophenyl)-1-piperazinyl]-, hydrochloride (1:1)
EINECS	Contact for details

Quality Control

Our Piperazine, 1-(3-Azetidinyl)-4-(4-Fluorophenyl)-, Hydrochloride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and support regulatory filings. Certificates of Analysis (COA) detailing purity, impurities, and other critical parameters are available for every lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.