Description

1-[3-(4-p-Tolyl-Piperazin-1-Yl)-Azetidin-1-Yl]-Ethanone is a sophisticated organic compound featuring a piperazine-azetidine core structure, serving as a critical building block in advanced pharmaceutical research and development. This compound matters because it provides a versatile chemical scaffold for medicinal chemists to explore novel therapeutic agents, particularly in the central nervous system (CNS) and receptor-targeted drug discovery. Pharmaceutical R&D laboratories and fine chemical manufacturers need this high-purity intermediate to synthesize and screen new drug candidates.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel drug candidates targeting neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Ligand Synthesis: Employed in the synthesis of selective ligands for receptor binding assays, particularly for serotonin and dopamine receptor subtypes.
• Chemical Biology Probes: Serves as a starting material for creating tool compounds to study biological pathways and protein functions.
• Fine Chemical Synthesis: Utilized in custom synthesis and contract manufacturing for producing specialized, high-value organic molecules.

Basic Information

Product Name	1-[3-(4-p-Tolyl-Piperazin-1-Yl)-Azetidin-1-Yl]-Ethanone
CAS No.	223381-96-2
Molecular Formula	C16H23N3O
Molecular Weight	273.38 g/mol
Synonyms	1-[3-[4-(4-Methylphenyl)-1-piperazinyl]-1-azetidinyl]ethanone; 1-[3-[4-(4-Methylphenyl)piperazin-1-yl]azetidin-1-yl]ethanone; 1-(3-(4-(p-Tolyl)piperazin-1-yl)azetidin-1-yl)ethanone; N-(4-Methylphenyl)-N'-(1-acetylazetidin-3-yl)piperazine; 223381-96-2; p-Tolylpiperazine azetidine ketone derivative
EINECS	Contact for details

Quality Control

Our 1-[3-(4-p-Tolyl-Piperazin-1-Yl)-Azetidin-1-Yl]-Ethanone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Any single impurity ≤ 1.0%
Total Impurities	≤ 3.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.