Description

n-T-Butyl-3-(4-(p-Methylphenyl)Piperazinyl)Azetidine is a high-purity, specialized organic compound with a complex heterocyclic structure, serving as a critical advanced intermediate in modern chemical synthesis. Its value lies in enabling the development of novel pharmacologically active molecules, particularly within central nervous system (CNS) research and drug discovery. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality building blocks for complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel drug candidates, particularly those targeting neurological receptors.
• Chemical Research & Development: Used in academic and industrial R&D for exploring new chemical entities and reaction pathways.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and medicinal chemistry studies.
• Agrochemical Intermediate: Potential use in the synthesis of advanced crop protection agents requiring specific nitrogen-containing heterocycles.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	n-T-Butyl-3-(4-(p-Methylphenyl)Piperazinyl)Azetidine
CAS No.	223381-88-2
Molecular Formula	C18H29N3
Molecular Weight	287.45 g/mol
Synonyms	1-tert-Butyl-3-[4-(4-methylphenyl)piperazin-1-yl]azetidine; 3-[4-(4-Methylphenyl)-1-piperazinyl]-1-(1,1-dimethylethyl)azetidine; 1-(tert-Butyl)-3-[4-(p-tolyl)piperazin-1-yl]azetidine; n-T-Butyl-3-(4-(p-Tolyl)Piperazinyl)Azetidine; 223381-88-2; tert-Butyl 3-(4-(p-tolyl)piperazin-1-yl)azetidine-1-carboxylate (related precursor)
EINECS	Contact for details

Quality Control

Our n-T-Butyl-3-(4-(p-Methylphenyl)Piperazinyl)Azetidine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis by GC. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.