Description

3-[4-(2-Methoxyphenyl)Piperazinyl]Azetidine Trihydrochloride is a high-purity, complex organic salt used as a critical intermediate in advanced pharmaceutical synthesis. This compound matters for its role in the research and development of novel therapeutic agents, particularly those targeting the central nervous system. It is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in producing active pharmaceutical ingredients (APIs) and reference standards.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly for neurological and psychiatric disorders.
• Chemical Research: Used as a reference standard and precursor in medicinal chemistry for structure-activity relationship (SAR) studies.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core structural component in the development of new APIs.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for pharmacological and biochemical research.

Basic Information

Product Name	3-[4-(2-Methoxyphenyl)Piperazinyl]Azetidine Trihydrochloride
CAS No.	223381-69-9
Molecular Formula	C14H22N3O • 3HCl
Molecular Weight	376.72 g/mol (Free base: 248.35 g/mol)
Synonyms	1-(2-Methoxyphenyl)-4-(azetidin-3-yl)piperazine trihydrochloride; 3-[4-(2-Methoxyphenyl)-1-piperazinyl]azetidine trihydrochloride; 2-Methoxyphenylpiperazinyl azetidine trihydrochloride; L-741,626 precursor; Dopamine D2 receptor antagonist intermediate; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 3-[4-(2-Methoxyphenyl)Piperazinyl]Azetidine Trihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.