Description

Ragaglitazar is a potent, dual-acting peroxisome proliferator-activated receptor (PPAR) agonist, specifically targeting the alpha and gamma subtypes. This compound is of significant interest in pharmaceutical research for its potential to modulate lipid and glucose metabolism. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutics for metabolic disorders such as type 2 diabetes and dyslipidemia.

Application

• Pharmaceutical Research & Development: Serves as a key reference standard and active pharmaceutical ingredient (API) in preclinical and clinical studies for metabolic diseases.
• Mechanism of Action Studies: Used to investigate the dual PPARα/γ agonism pathway and its effects on gene expression related to insulin sensitization and lipid regulation.
• Analytical Method Development: Employed as a high-purity standard for developing and validating HPLC, LC-MS, and other analytical techniques in quality control laboratories.
• Formulation Development: Acts as a critical component in the development of dosage forms for experimental therapeutic agents.
• Biochemical Screening: Utilized in high-throughput screening assays to identify and evaluate new compounds with similar or improved pharmacological profiles.

Basic Information

Product Name	Ragaglitazar
CAS No.	222834-22-2
Molecular Formula	C₁₉H₁₈N₂O₃S
Molecular Weight	354.42 g/mol
Synonyms	DRF 2725; (2S)-2-Ethoxy-3-[4-[2-(4-methanesulfonyloxyphenyl)ethoxy]phenyl]propanoic acid; (S)-2-Ethoxy-3-[4-[2-(4-methanesulfonyloxyphenyl)ethoxy]phenyl]propionic acid; Ragaglitazarum; Ragaglitazaro; Ragaglitazaro [Spanish]; Ragaglitazaro [Latin]; Ragaglitazaro [INN-Spanish]
EINECS	Contact for details

Quality Control

Our Ragaglitazar is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identity confirmation by spectroscopic methods (IR, NMR, MS), purity assessment by HPLC, and determination of residual solvents and related substances. A Certificate of Analysis (COA) detailing all test results and specifications is provided with every shipment to ensure traceability and compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature, typically between 15-25°C (59-77°F). The product is hygroscopic (moisture-sensitive) and should be kept in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Any single unknown impurity	≤0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.