Description

Tomopenem is a carbapenem-class β-lactam antibiotic with a broad spectrum of antibacterial activity. This compound is a critical intermediate in the synthesis of advanced pharmaceutical agents, valued for its potent efficacy against a wide range of Gram-positive and Gram-negative bacteria. It is primarily utilized by pharmaceutical manufacturers and research institutions engaged in the development of next-generation antibacterial drugs and novel therapeutic formulations.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel carbapenem antibiotics.
• Antibacterial Drug Development: Used in R&D for creating new therapeutic agents targeting resistant bacterial strains.
• Clinical Research: Employed in preclinical and clinical studies to evaluate new antibacterial therapies.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method validation in laboratories.
• Biochemical Research: Utilized in studies investigating bacterial cell wall synthesis and β-lactamase inhibition mechanisms.

Basic Information

Product Name	Tomopenem
CAS No.	222400-20-6
Molecular Formula	C16H21N5O7S2
Molecular Weight	483.50 g/mol
Synonyms	(1R,5S,6S)-6-[(1R)-1-Hydroxyethyl]-2-[(3S,5S)-5-[(sulfamoylamino)methyl]pyrrolidin-3-yl]thio]-1-methyl-1-carbapen-2-em-3-carboxylic acid; Tomopenem (antibiotic); (4R,5S,6S)-3-[[(3S,5S)-5-[[(Aminosulfonyl)amino]methyl]-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid; Ro 63-9141; CS-023
EINECS	Contact for details

Quality Control

Our Tomopenem is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%
Bacterial Endotoxins	< 0.50 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.