Description

Lumiracoxib CAS NO 220991-20-8 is a selective cyclooxygenase-2 (COX-2) inhibitor belonging to the class of nonsteroidal anti-inflammatory drugs (NSAIDs). This compound is of significant interest in pharmaceutical research and development for its targeted mechanism of action. It is primarily utilized by pharmaceutical manufacturers and research institutions engaged in the development of novel analgesic and anti-inflammatory therapeutics.

Application

• Pharmaceutical Active Ingredient (API): Serves as the core active component in the formulation of prescription medications targeting pain and inflammation.
• Analgesic Research: A key reference standard and investigational compound in preclinical and clinical studies for managing acute and chronic pain conditions.
• Anti-inflammatory Drug Development: Used in R&D for creating new treatments for arthritis, osteoarthritis, and other inflammatory disorders with a focus on improved gastrointestinal safety profiles.
• Biochemical Research: Employed as a selective tool in pharmacological studies to understand COX-2 enzyme pathways and their role in disease states.
• Reference Standard: Provides a high-purity benchmark for quality control, analytical method development, and regulatory submissions in pharmaceutical laboratories.
• Formulation Studies: Used in the development of various dosage forms, optimizing stability, bioavailability, and efficacy of the final drug product.

Basic Information

Product Name	Lumiracoxib
CAS No.	220991-20-8
Molecular Formula	C15H13ClFNO2
Molecular Weight	293.72 g/mol
Synonyms	2-[(2-Chloro-6-fluorophenyl)amino]-5-methylbenzeneacetic acid; Prexige; COX-189; UNII-6U1NE8Q6US; 4-[4-(Methylsulfonyl)phenyl]-3-phenyl-5H-furan-2-one (Note: This is a common structural core descriptor); Lumiracoxibum; (2-[(2-Chloro-6-fluorophenyl)amino]-5-methylphenyl)acetic acid
EINECS	Contact for details

Quality Control

Our Lumiracoxib is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided to guarantee traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.