Description

1-Boc-7-Phenyl-1,4-Diazepane is a high-purity, protected diazepane derivative, serving as a critical chiral building block in advanced organic synthesis. Its value lies in providing a versatile nitrogen-containing scaffold for constructing complex molecules with high stereochemical control. This intermediate is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of new therapeutic agents, including central nervous system (CNS) drugs and enzyme inhibitors.
• Agrochemical Synthesis: Building block for creating novel pesticides and herbicides with specific biological activity.
• Ligand and Catalyst Development: Precursor for synthesizing chiral ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Peptidomimetic Research: Used in the design and synthesis of peptide analogs and conformationally restricted scaffolds for drug discovery.
• Academic & R&D Laboratories: Serves as a valuable starting material for methodological studies in organic chemistry and medicinal chemistry programs.
• Custom Synthesis: Foundation for the contract manufacturing of specialized, high-value fine chemicals and advanced intermediates.

Basic Information

Product Name	1-Boc-7-Phenyl-1,4-Diazepane
CAS No.	220898-23-7
Molecular Formula	C₁₆H₂₄N₂O₂
Molecular Weight	276.37 g/mol
Synonyms	1-tert-Butoxycarbonyl-7-phenyl-1,4-diazepane; 7-Phenyl-1,4-diazepane-1-carboxylic acid tert-butyl ester; tert-Butyl 7-phenyl-1,4-diazepane-1-carboxylate; 1-Boc-7-phenylperhydro-1,4-diazepine; 1,4-Diazepane, 7-phenyl-, 1-(1,1-dimethylethyl) ester; Boc-7-phenyl-1,4-diazepane; 1-N-Boc-7-phenyl-1,4-diazepane
EINECS	Contact for details

Quality Control

Our 1-Boc-7-Phenyl-1,4-Diazepane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure it meets the high standards required for pharmaceutical R&D and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.