Description

1-Benzyl-2(S)-Isopropyl-Piperazine is a chiral piperazine derivative of significant interest in advanced organic synthesis. This compound serves as a crucial chiral building block and intermediate for the development of active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with specific stereochemical configurations.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral therapeutic areas.
• Asymmetric Catalyst Ligand Precursor: Used in the preparation of chiral ligands for asymmetric catalysis, enabling enantioselective synthesis.
• Agrochemical Research: Serves as a building block for developing new chiral pesticides and herbicides with improved efficacy and selectivity.
• Fine Chemical Synthesis: Employed in the multistep synthesis of complex, high-value specialty chemicals requiring specific stereocenters.
• Academic & R&D: Utilized in university and corporate research laboratories for methodological studies in organic and medicinal chemistry.
• Custom Synthesis Projects: A starting material for contract research and manufacturing organizations (CROs/CMOs) working on client-specific molecular targets.

Basic Information

Product Name	1-Benzyl-2(S)-Isopropyl-Piperazine
CAS No.	220663-44-5
Molecular Formula	C14H22N2
Molecular Weight	218.34 g/mol
Synonyms	(S)-1-Benzyl-2-isopropylpiperazine; (S)-2-Isopropyl-1-benzylpiperazine; 1-Benzyl-2-[(2S)-propan-2-yl]piperazine; 2(S)-Isopropyl-1-benzylpiperazine; (S)-1-Benzyl-2-(1-methylethyl)piperazine; (S)-1-Benzyl-2-(propan-2-yl)piperazine; 220663-44-5; B2IP
EINECS	Contact for details

Quality Control

Our 1-Benzyl-2(S)-Isopropyl-Piperazine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, confirming identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Enantiomeric Excess)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.