Description

Cimicifugic Acid F is a bioactive triterpenoid glycoside primarily isolated from the *Cimicifuga* (Actaea) genus of plants. This compound is of significant interest for its role as a key chemical marker and active constituent in botanical extracts, directly impacting product standardization and efficacy. It is essential for manufacturers and researchers in the pharmaceutical, nutraceutical, and botanical extract industries who require high-purity reference standards and raw materials for quality control, research, and product development.

Application

• Pharmaceutical Reference Standard: Used as a high-purity certified reference material (CRM) for the identification and quantification of Cimicifugic Acid F in drug substances and finished products.
• Botanical Extract Standardization: Serves as a critical marker compound for the quality control and standardization of Black Cohosh (*Actaea racemosa*) and related herbal extracts to ensure batch-to-batch consistency.
• Nutraceutical & Dietary Supplement Formulation: Incorporated as a characterized active ingredient in supplements targeting women's health, leveraging its association with traditional uses of Black Cohosh.
• Biomedical & Pharmacological Research: Utilized in *in vitro* and *in vivo* studies to investigate potential biological activities, mechanisms of action, and metabolic pathways.
• Analytical Method Development: Employed as an analytical standard for developing and validating HPLC, UPLC, and LC-MS methods in quality control laboratories.
• Cosmeceutical Ingredients: Potential application in advanced skincare formulations where standardized plant-derived actives are required.

Basic Information

Product Name	Cimicifugic Acid F
CAS No.	220618-91-7
Molecular Formula	C37H56O11
Molecular Weight	700.84 g/mol
Synonyms	23-Epi-26-deoxyactein; (23R)-26-Deoxyactein; Cimicifugic acid F; 26-Deoxyactein; 23-Epi-26-deoxyactein; 3β,12β,23-Trihydroxy-16,23-epoxy-24,25,26,27-tetranor-9,19-cyclolanost-22(29)-en-11-one 3-O-β-D-xylopyranoside
EINECS	Contact for details

Quality Control

Our Cimicifugic Acid F is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, MS), to ensure it meets the high standards required for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and analytical methods is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. Due to its hygroscopic nature, the container must be kept tightly sealed in a controlled low-humidity environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥95.0%
Loss on Drying	≤2.0%
Residue on Ignition	≤0.5%
Heavy Metals	≤20 ppm
Solvent Residues	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.