Description

(4As,8As)-Decahydro-1,5-Naphthyridine CAS NO 219522-28-8 is a saturated, bicyclic organic compound featuring a naphthyridine core structure. This specialized heterocyclic scaffold is of significant value as a key intermediate and building block in advanced organic synthesis. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for constructing complex molecular architectures, particularly in medicinal chemistry programs targeting novel therapeutics.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds with complex polycyclic frameworks.
• Agrochemical Research: Used as a building block for developing new herbicides, fungicides, and insecticides with novel modes of action.
• Ligand Synthesis: Employed in the preparation of chiral ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized to create molecular probes for studying enzyme function and biological pathways.
• Material Science: Acts as a monomer or precursor for specialty polymers and advanced organic materials.
• Academic & Contract Research: Essential for fundamental organic chemistry research and custom synthesis projects in CROs (Contract Research Organizations).

Basic Information

Product Name	(4As,8As)-Decahydro-1,5-Naphthyridine
CAS No.	219522-28-8
Molecular Formula	C8H16N2
Molecular Weight	140.23 g/mol
Synonyms	(4aR,8aR)-Decahydro-1,5-naphthyridine; (4aR,8aR)-Octahydro-1,5-naphthyridine; 1,5-Diazadecalin; Perhydro-1,5-naphthyridine; 1,5-Naphthyridine, decahydro-, (4aR,8aR)-; Bicyclo[4.4.0]decane, 1,5-diaza-; (4aR,8aR)-1,5-Diazadecalin
EINECS	Contact for details

Quality Control

Our (4As,8As)-Decahydro-1,5-Naphthyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, and custom purity grades (e.g., >97%, >98%, >99%) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.