Description

α,α-Diphenyl-4-[(3-Pyridinylmethylene)Amino]-1-Piperazinepentanenitrile is a specialized organic compound featuring a complex molecular architecture that combines piperazine, diphenyl, and pyridine moieties. This structure makes it a valuable advanced pharmaceutical intermediate and a key building block in medicinal chemistry research. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel bioactive molecules. The compound's design facilitates its role in the development of potential therapeutic agents targeting central nervous system and other disorders.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of novel drug candidates, particularly in neuroscience and psychiatric drug discovery.
• Medicinal Chemistry Research: Used as a sophisticated scaffold or building block for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Biochemical Tool Compound: Employed in academic and industrial research to study biological pathways and enzyme interactions due to its specific structural features.
• Fine Chemical Synthesis: Acts as a key raw material for the custom synthesis of complex, high-value specialty chemicals for advanced applications.
• Contract Research & Manufacturing (CRAM): Supplied to organizations offering custom synthesis and process development services for the pharmaceutical industry.

Basic Information

Product Name	α,α-Diphenyl-4-[(3-Pyridinylmethylene)Amino]-1-Piperazinepentanenitrile
CAS No.	218136-59-5
Molecular Formula	C27H27N5
Molecular Weight	421.54 g/mol
Synonyms	4-[(3-Pyridinylmethylene)amino]-α,α-diphenyl-1-piperazinepentanenitrile; 1-Piperazinepentanenitrile, α,α-diphenyl-4-[(3-pyridinylmethylene)amino]-; α,α-Diphenyl-4-[(pyridin-3-ylmethylidene)amino]piperazine-1-pentanenitrile; GSK-3 Inhibitor XIII (historical context); CAS 218136-59-5
EINECS	Contact for details

Quality Control

Our production of α,α-Diphenyl-4-[(3-Pyridinylmethylene)Amino]-1-Piperazinepentanenitrile adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for research applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to minimize moisture uptake and ensure long-term stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.