Description

4-Methyl-2-(2-Pyrazinyl)-1,3-Thiazole-5-Carboxylic Acid is a heterocyclic carboxylic acid building block of significant interest in advanced organic synthesis. Its molecular architecture, featuring both pyrazine and thiazole rings, makes it a valuable intermediate for constructing complex pharmacologically active molecules. This compound is primarily utilized by research institutions and pharmaceutical development companies engaged in medicinal chemistry and the synthesis of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the research and development of new drug candidates, particularly in oncology and antiviral therapeutic areas.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Development: Acts as a building block for synthesizing novel herbicides, fungicides, and insecticides with potential new modes of action.
• Material Science: Investigated for the synthesis of specialized ligands in coordination chemistry and for creating advanced organic electronic materials.
• Chemical Biology: Employed in the design and synthesis of molecular probes and inhibitors for studying biological pathways and enzyme functions.

Basic Information

Product Name	4-Methyl-2-(2-Pyrazinyl)-1,3-Thiazole-5-Carboxylic Acid
CAS No.	216959-92-1
Molecular Formula	C9H7N3O2S
Molecular Weight	221.24 g/mol
Synonyms	4-Methyl-2-(pyrazin-2-yl)-1,3-thiazole-5-carboxylic acid; 2-(2-Pyrazinyl)-4-methyl-5-thiazolecarboxylic acid; 5-Thiazolecarboxylic acid, 4-methyl-2-(2-pyrazinyl)-; 4-Methyl-2-pyrazin-2-yl-1,3-thiazole-5-carboxylic acid; 216959-92-1; 4-Methyl-2-(2-pyridazinyl)-1,3-thiazole-5-carboxylic acid (common alternate spelling)
EINECS	Contact for details

Quality Control

Our production of 4-Methyl-2-(2-Pyrazinyl)-1,3-Thiazole-5-Carboxylic Acid adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the exacting standards required for research and development applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.