Description

(2R,5S)-1-Benzyl-2,5-Dimethylpiperazine is a chiral piperazine derivative of significant importance in advanced organic synthesis. This compound serves as a versatile and high-value building block for the development of active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors, where its defined stereochemistry is critical for creating molecules with specific biological activity.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug candidates, particularly those targeting neurological and infectious diseases.
• Asymmetric Catalyst Ligand: Used to construct chiral ligands for metal-catalyzed asymmetric reactions, enhancing enantioselectivity.
• Agrochemical Research: Serves as a precursor in the development of novel pesticides and herbicides with improved efficacy and selectivity.
• Chemical Biology Probe: Employed in medicinal chemistry to study protein-ligand interactions and structure-activity relationships (SAR).
• Fine Chemical Synthesis: A valuable intermediate for creating specialty chemicals with applications in material science and electronics.

Basic Information

Product Name	(2R,5S)-1-Benzyl-2,5-Dimethylpiperazine
CAS No.	216532-43-3
Molecular Formula	C13H20N2
Molecular Weight	204.31 g/mol
Synonyms	(2R,5S)-1-Benzyl-2,5-dimethylpiperazine; 1-Benzyl-2,5-dimethylpiperazine, (2R,5S)-; (2R,5S)-1-Benzyl-2,5-dimethyl-piperazine; (R,S)-1-Benzyl-2,5-dimethylpiperazine (specific isomer); Bn-2,5-DMP; 1-(Phenylmethyl)-2,5-dimethylpiperazine, (2R,5S)-; Piperazine, 1-benzyl-2,5-dimethyl-, (2R,5S)-
EINECS	Contact for details

Quality Control

Our (2R,5S)-1-Benzyl-2,5-Dimethylpiperazine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric purity and NMR for structural confirmation, to ensure compliance with exacting research and pharmaceutical-grade standards. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.