Description

1-(2-Chloro-6-Fluorobenzyl)Piperazine is a versatile and high-value pharmaceutical intermediate and building block in organic synthesis. This compound is critical for the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for its role in creating new chemical entities.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-infective research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides requiring specific halogenated benzylpiperazine motifs.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Research & Development: A valuable reagent for medicinal chemistry programs and structure-activity relationship (SAR) studies.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals.
• Reference Standard: Supplied as a high-purity analytical standard for quality control and regulatory testing in API manufacturing.

Basic Information

Product Name	1-(2-Chloro-6-Fluorobenzyl)Piperazine
CAS No.	215655-20-2
Molecular Formula	C11H14ClFN2
Molecular Weight	228.70 g/mol
Synonyms	1-[(2-Chloro-6-fluorophenyl)methyl]piperazine; 2-Chloro-6-fluorobenzylpiperazine; Piperazine, 1-[(2-chloro-6-fluorophenyl)methyl]-; 215655-20-2; (2-Chloro-6-fluorobenzyl)piperazine; 1-(2-Chloro-6-fluorobenzyl)-piperazine; 1-(2-Chloro-6-fluorobenzyl)piperazine hydrochloride (salt forms may vary)
EINECS	Contact for details

Quality Control

Our 1-(2-Chloro-6-Fluorobenzyl)Piperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.