Description

1-(3-Bromephenyl)-Piperazin-2-One Hcl is a high-purity organic compound, specifically a halogenated piperazinone derivative, serving as a critical building block in advanced chemical synthesis. This compound is valued for its role as a versatile intermediate in the research and development of novel active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides that require a brominated phenylpiperazinone scaffold.
• Chemical Biology Probe Synthesis: Employed in creating specialized molecules for studying biological pathways and protein interactions.
• Material Science Research: Acts as a monomer or functionalizing agent in the development of advanced polymers with specific electronic or binding properties.
• Contract Research & Development (CRO/CMO): Supplied to organizations engaged in custom synthesis and process optimization for client projects.

Basic Information

Product Name	1-(3-Bromephenyl)-Piperazin-2-One Hcl
CAS No.	215649-81-3
Molecular Formula	C10H12BrN2O·HCl
Molecular Weight	307.58 g/mol (HCl salt)
Synonyms	1-(3-Bromophenyl)piperazin-2-one hydrochloride; 3-Bromo-1-(2-oxopiperazin-1-yl)benzene hydrochloride; 1-(3-Bromophenyl)-2-piperazinone hydrochloride; 1-(m-Bromophenyl)piperazin-2-one HCl; 215649-81-3 (CAS); 1-(3-Bromophenyl)-1,4-diazepan-2-one hydrochloride (tautomeric form); 3-Bromo-N-(2-oxopiperazin-1-yl)aniline hydrochloride
EINECS	Contact for details

Quality Control

Our 1-(3-Bromephenyl)-Piperazin-2-One Hcl is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the stringent requirements for research and development use. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.