Description

1-(3-(Trifluoromethoxy)Phenyl) Piperazin-2-One Hydrochloride is a high-purity, synthetically derived organic compound belonging to the piperazine class. This chemical is a crucial pharmaceutical intermediate and research chemical, valued for its role in the development of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of complex molecules for therapeutic applications.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly in central nervous system (CNS) and psychiatric disorder research.
• Chemical Research & Development: Used as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Academic Research: Employed in university and institutional labs for studying heterocyclic chemistry and novel synthetic pathways.
• Precursor for Agrochemicals: Potential use in the development of advanced crop protection agents and specialty agrochemicals.

Basic Information

Product Name	1-(3-(Trifluoromethoxy)Phenyl) Piperazin-2-One Hydrochloride
CAS No.	215649-79-9
Molecular Formula	C11H12F3N2O2 • HCl
Molecular Weight	296.69 g/mol (Free base: 260.22 g/mol)
Synonyms	1-[3-(Trifluoromethoxy)phenyl]piperazin-2-one hydrochloride; 1-(3-Trifluoromethoxyphenyl)-2-piperazinone hydrochloride; 2-Piperazinone, 1-[3-(trifluoromethoxy)phenyl]-, hydrochloride; 215649-79-9; 1-(3-(Trifluoromethoxy)phenyl)piperazin-2-one HCl; 3-(Trifluoromethoxy)phenyl piperazinone hydrochloride
EINECS	Contact for details

Quality Control

Our 1-(3-(Trifluoromethoxy)Phenyl) Piperazin-2-One Hydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Production adheres to cGMP guidelines where applicable. Every batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, available upon request. We are committed to meeting the stringent requirements of pharmaceutical and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.