Description

2-[4-[5-Chloro-3-(Trifluoromethyl)-2-Pyridyl]Piperazino]Ethan-1-Ol is a high-purity, advanced pharmaceutical intermediate with a distinct heterocyclic structure. This compound matters for its critical role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular design. Pharmaceutical R&D teams and fine chemical manufacturers need this precise building block to develop next-generation medications, leveraging its unique piperazine and pyridine motifs.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, especially in central nervous system (CNS) and oncology targets.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the trifluoromethyl and chloro groups confer specific bioactivity.
• Ligand & Catalyst Development: Serves as a precursor for complex ligands in catalytic systems and metal-organic frameworks (MOFs).
• Biochemical Research: Employed in academic and industrial research for studying enzyme inhibition and receptor binding activities.
• Fine Chemical Production: An essential building block for manufacturing other specialized, high-value nitrogen-containing heterocycles.

Basic Information

Product Name	2-[4-[5-Chloro-3-(Trifluoromethyl)-2-Pyridyl]Piperazino]Ethan-1-Ol
CAS No.	215434-39-2
Molecular Formula	C12H15ClF3N3O
Molecular Weight	309.72 g/mol
Synonyms	5-Chloro-3-(trifluoromethyl)-2-[4-(2-hydroxyethyl)piperazin-1-yl]pyridine; 1-(2-Hydroxyethyl)-4-[5-chloro-3-(trifluoromethyl)-2-pyridyl]piperazine; 2-(4-(5-Chloro-3-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)ethanol; 215434-39-2; CAS 215434-39-2
EINECS	Contact for details

Quality Control

Our 2-[4-[5-Chloro-3-(Trifluoromethyl)-2-Pyridyl]Piperazino]Ethan-1-Ol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting full specifications are provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.