Description

Ethyl 3-(4-Methylpiperazin-1-Yl)Benzoate is a high-purity pharmaceutical intermediate featuring a benzoate ester core linked to a substituted piperazine moiety. This compound is valued for its role as a versatile building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research. It is primarily sought by pharmaceutical R&D laboratories, fine chemical manufacturers, and contract development and manufacturing organizations (CDMOs) engaged in innovative drug development.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates, especially those targeting neurological receptors.
• API Synthesis: Used in constructing the molecular framework for potential antipsychotic, antidepressant, or anti-cancer agents.
• Chemical Research: Serves as a valuable scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Fine Chemical Production: Employed in custom synthesis and scale-up processes for specialized, high-value chemical entities.
• Reference Standard: Can be supplied as a certified reference material for analytical method development and quality control in pharmaceutical analysis.

Basic Information

Product Name	Ethyl 3-(4-Methylpiperazin-1-Yl)Benzoate
CAS No.	215315-89-2
Molecular Formula	C14H20N2O2
Molecular Weight	248.32 g/mol
Synonyms	Ethyl 3-(4-Methyl-1-piperazinyl)benzoate; 3-(4-Methylpiperazin-1-yl)benzoic acid ethyl ester; Benzoic acid, 3-(4-methyl-1-piperazinyl)-, ethyl ester; 1-[3-(Ethoxycarbonyl)phenyl]-4-methylpiperazine
EINECS	Contact for details

Quality Control

Our Ethyl 3-(4-Methylpiperazin-1-Yl)Benzoate is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the stringent requirements for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.