Description

3-Azabicyclo[4.2.0]Octan-4-One,(1R,6R)-Rel-(9Ci) is a high-purity, stereochemically defined bicyclic lactam building block of significant interest in advanced organic synthesis. This compound matters as a versatile chiral scaffold for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by medicinal chemists and process R&D teams in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Medicinal Chemistry Research: Serves as a constrained scaffold for exploring structure-activity relationships (SAR) and improving the pharmacokinetic properties of lead compounds.
• Asymmetric Synthesis: Utilized in stereoselective reactions to introduce complex, rigid bicyclic frameworks into target molecules.
• Agrochemical Synthesis: Intermediate in the development of advanced, chiral active ingredients for crop protection.
• Chemical Biology Probes: Used to create specialized molecular tools for studying enzyme mechanisms and biological pathways.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and novel compound library generation.

Basic Information

Product Name	3-Azabicyclo[4.2.0]Octan-4-One,(1R,6R)-Rel-(9Ci)
CAS No.	214479-57-9
Molecular Formula	C7H11NO
Molecular Weight	125.17 g/mol
Synonyms	(1R,6R)-3-Azabicyclo[4.2.0]octan-4-one; rel-(1R,6R)-3-Azabicyclo[4.2.0]octan-4-one; (1R,6R)-rel-3-Azabicyclo[4.2.0]octan-4-one; Bicyclic β-lactam; 3-Azabicyclo[4.2.0]octan-4-one, (1R,6R)-rel-; Azabicyclooctanone derivative; Chiral bicyclic lactam
EINECS	Contact for details

Quality Control

Our 3-Azabicyclo[4.2.0]Octan-4-One,(1R,6R)-Rel-(9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity determination, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, GC) are provided for every shipment, confirming identity, purity, and stereochemical integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.