Description

5-Chloropyrido[4,3-B]Pyrazine is a high-value heterocyclic building block and advanced pharmaceutical intermediate. This compound matters for its crucial role in the synthesis of complex molecules, particularly in medicinal chemistry for developing new therapeutic agents. It is primarily needed by research institutions and pharmaceutical companies engaged in drug discovery, especially for projects targeting kinase inhibitors and other biologically active nitrogen-containing heterocycles.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in oncology and CNS research.
• Kinase Inhibitor Development: Serves as a core scaffold for designing and synthesizing potent and selective kinase inhibitors.
• Agrochemical Research: Used in the discovery of new active ingredients for crop protection products.
• Material Science: Investigated as a building block for organic electronic materials and ligands in catalysis.
• Academic & Contract Research: Essential for synthetic chemistry research in universities and CROs (Contract Research Organizations).
• Custom Synthesis: A starting material for the custom manufacturing of complex, high-value specialty chemicals.

Basic Information

Product Name	5-Chloropyrido[4,3-B]Pyrazine
CAS No.	214045-82-6
Molecular Formula	C7H4ClN3
Molecular Weight	165.58 g/mol
Synonyms	5-Chloro[4,3-b]pyridopyrazine; 5-Chloro-pyrido[4,3-b]pyrazine; 5-Chloro-4-azaindolizine; 5-Chloro-1,5-naphthyridine; 5-Chloro-pyrido[4,3-b]pyrazin; 5-Chloro-4-azanaphthalene
EINECS	Contact for details

Quality Control

Our 5-Chloropyrido[4,3-B]Pyrazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.