Description

3-[(2,3-Dihydro-5-Methoxy-1H-Inden-4-Yl)Oxy]-Pyrrolidine Hydrochloride is a high-purity, non-racemic chiral building block and pharmaceutical intermediate of significant synthetic value. Its core value proposition lies in its defined stereochemistry and functional group arrangement, which is critical for constructing complex bioactive molecules with high enantiomeric purity. This compound is essential for research and development chemists in the pharmaceutical and fine chemical industries, particularly those focused on central nervous system (CNS) agents and novel therapeutic candidates.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel drug candidates, particularly for neurological and psychiatric disorders.
• Asymmetric Synthesis: Used as a building block in the stereoselective construction of complex organic molecules requiring a specific enantiomeric form.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization programs to develop new active pharmaceutical ingredients (APIs).
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in API manufacturing.
• Chemical Biology Probes: Utilized in the development of tool compounds for studying biological pathways and target validation.

Basic Information

Product Name	3-[(2,3-Dihydro-5-Methoxy-1H-Inden-4-Yl)Oxy]-Pyrrolidine Hydrochloride
CAS No.	213007-95-5
Molecular Formula	C14H20ClNO2
Molecular Weight	269.77 g/mol
Synonyms	3-[(5-Methoxy-2,3-dihydro-1H-inden-4-yl)oxy]pyrrolidine hydrochloride; 4-(3-Pyrrolidinyloxy)-5-methoxyindane hydrochloride; (R/S)-3-((5-Methoxy-2,3-dihydro-1H-inden-4-yl)oxy)pyrrolidine HCl; Pyrrolidine, 3-[(5-methoxy-2,3-dihydro-1H-inden-4-yl)oxy]-, hydrochloride (1:1)
EINECS	Contact for details

Quality Control

Our 3-[(2,3-Dihydro-5-Methoxy-1H-Inden-4-Yl)Oxy]-Pyrrolidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity determination, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.