Description

6-Chloro-3-(2,3-Dichlorophenyl)Pyrazin-2-Amine is a high-purity, halogenated pyrazine derivative serving as a critical advanced pharmaceutical intermediate. Its value lies in its precise molecular architecture, which enables the synthesis of novel active pharmaceutical ingredients (APIs) with targeted therapeutic effects. This compound is essential for research and development chemists and process scale-up teams in the pharmaceutical and agrochemical industries, particularly those focused on creating new small-molecule drugs and crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and fungicides, leveraging its halogenated aromatic structure.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry & Scale-Up: Employed in pilot plant and commercial manufacturing processes for API production under current Good Manufacturing Practices (cGMP).
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and impurity profiling.

Basic Information

Product Name	6-Chloro-3-(2,3-Dichlorophenyl)Pyrazin-2-Amine
CAS No.	212779-33-4
Molecular Formula	C10H6Cl3N3
Molecular Weight	282.53 g/mol
Synonyms	2-Amino-6-chloro-3-(2,3-dichlorophenyl)pyrazine; 6-Chloro-3-(2,3-dichlorophenyl)-2-pyrazinamine; 2,3-Dichloro-6-chloropyrazin-2-amine; (2,3-Dichlorophenyl)-6-chloropyrazin-2-amine; 212779-33-4; 6-Chloro-3-(2,3-dichlorophenyl)pyrazin-2-ylamine
EINECS	Contact for details

Quality Control

Every batch of 6-Chloro-3-(2,3-Dichlorophenyl)Pyrazin-2-Amine is manufactured and tested under a strict quality management system. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards and customer-specific requirements. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and away from direct light sources to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.