Description

1-(5-Chloro-2-Fluoro-4-Nitro-Phenyl)-Piperazine is a high-purity, functionalized piperazine derivative of significant importance in advanced organic synthesis. This compound serves as a critical building block for pharmaceutical research and development, particularly in the creation of novel active pharmaceutical ingredients (APIs). It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders, antimicrobial agents, and oncology therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its halogenated aromatic structure for bioactivity.
• Chemical Biology & Proteomics: Employed as a scaffold or linker in the design of molecular probes and tool compounds for studying biological pathways.
• Material Science: Serves as a monomer or functionalizing agent in the synthesis of advanced polymers and specialty materials with tailored properties.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing complex molecules for clients.

Basic Information

Product Name	1-(5-Chloro-2-Fluoro-4-Nitro-Phenyl)-Piperazine
CAS No.	212694-66-1
Molecular Formula	C10H11ClFN3O2
Molecular Weight	259.67 g/mol
Synonyms	1-(5-Chloro-2-fluoro-4-nitrophenyl)piperazine; 5-Chloro-2-fluoro-4-nitro-1-piperazinobenzene; 4-Nitro-5-chloro-2-fluorophenylpiperazine; Piperazine, 1-(5-chloro-2-fluoro-4-nitrophenyl)-; 212694-66-1; 5-Chloro-2-fluoro-4-nitrophenylpiperazine; 1-(5-Chloro-2-fluoro-4-nitro-phenyl)piperazine
EINECS	Contact for details

Quality Control

Our 1-(5-Chloro-2-Fluoro-4-Nitro-Phenyl)-Piperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light) as indicated by its chemical properties.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.