Description

Meropenem Sodium Salt is a broad-spectrum, carbapenem-class β-lactam antibiotic formulated for enhanced stability and solubility. This compound is critical for combating severe, multi-drug resistant bacterial infections, particularly in hospital settings. It is an essential active pharmaceutical ingredient (API) for the manufacture of injectable antibiotic formulations, primarily targeting the pharmaceutical and biotechnology industries for human therapeutic use.

Application

• Pharmaceutical API: Primary use as the active ingredient in sterile injectable formulations for intravenous or intramuscular administration.
• Hospital-Acquired Infections: Treatment of complicated intra-abdominal infections (cIAI), complicated skin and skin structure infections (cSSSI), and bacterial meningitis.
• Empirical Therapy: Used for febrile neutropenia and other severe infections where the causative pathogen is not immediately identified.
• Antibiotic Combination Drugs: Serves as a key component in combination therapies aimed at overcoming bacterial resistance mechanisms.
• Research & Development: Utilized in microbiological research, antimicrobial susceptibility testing, and the development of new antibacterial agents.
• Veterinary Medicine: Potential application in treating serious bacterial infections in animals, subject to regional regulatory approvals.

Basic Information

Product Name	Meropenem Sodium Salt
CAS No.	211238-34-5
Molecular Formula	C17H24N3NaO5S
Molecular Weight	405.45 g/mol
Synonyms	Meropenem Sodium; Meropenem Na; (4R,5S,6S)-3-[[(3S,5S)-5-(Dimethylcarbamoyl)-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic Acid Sodium Salt; SM-7338 Sodium; ICI-194660 Sodium; Merrem; Meronem; Antibiotic SM 7338 Sodium
EINECS	Contact for details

Quality Control

Our Meropenem Sodium Salt is manufactured and tested to meet high-purity pharmacopeial standards. Quality is assured through a comprehensive battery of analytical tests including HPLC for assay and related substances, residual solvent analysis, and microbiological examination. Certificates of Analysis (COA) documenting compliance with specifications are provided with each batch. We support requirements for cGMP and ICH Q7 guidelines for active pharmaceutical ingredients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C) or as specified. This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccated environment to maintain stability and potency. Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	White to slightly yellowish powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms to reference standard
Assay (HPLC, anhydrous basis)	98.0% - 102.0%
pH (1% solution)	6.5 - 8.5
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C
Bacterial Endotoxins	< 0.17 EU/mg
Sterility (for sterile grade)	Sterile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.