Description

2-Amino-3-Methyl-3H-Imidazo[4,5-F]Quinoline-2-13C is a stable isotope-labeled analog of a heterocyclic aromatic amine, specifically enriched with carbon-13 at the 2-position of the imidazole ring. This compound is critically important for use as an internal standard in advanced analytical techniques, enabling precise quantification and reliable data in complex matrices. It is primarily required by research institutions, pharmaceutical developers, and analytical laboratories engaged in metabolite identification, pharmacokinetic studies, and food safety testing for heterocyclic amines.

Application

• Internal Standard for Mass Spectrometry (MS): Essential for quantitative LC-MS/MS and GC-MS analysis in bioanalytical and environmental testing.
• Metabolite Tracing and Drug Metabolism Studies: Used in ADME (Absorption, Distribution, Metabolism, Excretion) research to track the fate of parent compounds.
• Food Safety and Contaminant Analysis: Enables accurate measurement of mutagenic heterocyclic aromatic amines (HAAs) in cooked proteinaceous foods.
• Toxicological Research: Supports studies on the genotoxicity and carcinogenicity of related amine compounds.
• Pharmaceutical Impurity Profiling: Aids in the identification and quantification of process-related impurities or degradants.
• Stable Isotope Labeling Assays: Serves as a critical reagent in the development of validated analytical methods requiring isotope dilution.

Basic Information

Product Name	2-Amino-3-Methyl-3H-Imidazo[4,5-F]Quinoline-2-13C
CAS No.	210049-11-9
Molecular Formula	C11H9N5 (with 13C at specified position)
Molecular Weight	Contact for details
Synonyms	2-Amino-3-methylimidazo[4,5-f]quinoline-2-13C; 2-13C-2-Amino-3,4-dimethylimidazo[4,5-f]quinoline (common mis-association); 2-13C-MeIQ; 2-Amino-3-methyl-3H-imidazo[4,5-f]quinoline (13C labeled); Isotopically labeled MeIQ; 13C-labeled HAA standard; 2-13C-2-Amino-3-methylimidazoquinoline
EINECS	Contact for details

Quality Control

Our isotope-labeled compounds are produced and handled under strict quality protocols to ensure isotopic purity and chemical integrity, which are paramount for analytical accuracy. Each batch is characterized by advanced spectroscopic methods (NMR, MS) to confirm isotopic enrichment and chemical identity. Certificates of Analysis (COA) are provided, detailing assay purity (by HPLC), isotopic enrichment, and other critical parameters, ensuring compliance with the stringent requirements of analytical and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be sealed under an inert atmosphere after opening and desiccated for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	Off-white to light brown powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Isotopic Enrichment	≥ 99 atom % 13C
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.